Pharmaceutical Tablets are solid dosage forms containing drug substances usually prepared with the aid of suitable pharmaceutical excipients. Here we mention a list of common pharmaceutical excipients used in tablet formulation.
A List of Excipients Used in Tablet Formulation
• Alginic Acid - 1 to 5% w/w (as both a binder and disintegrating agent)
• Alpha Tocopherol - 0.001 to 0.05% v/v (as an antioxidant for oil- or fat-based product)
• Aspartame – 180 to 200 times more sweetener than sucrose
• Butylated Hydroxyanisole – 0.01% (as an antioxidant)
• Butylated hydroxytoluene - 0.01 to 0.1% (as an antioxidant)
• Calcium Carbonate – amount may vary (as a diluent or bulking agent)
• Dibasic Calcium Phosphate - amount may vary (to improve compaction properties or flow properties)
• Calcium Stearate – up to 1.0% (as a lubricant)
• Carbomer – 0.75 to 3% (as a binder)
• Carbomer – 5 to 30% (as a control releasing agent)
• Carboxymethylcellulose Sodium - 1 to 6% (as a binder)
• Cellulose acetate phthalate (CAP) – 0.5 to 9% (as a coating agent)
• Croscarmellose Sodium – up to 5% (as a disintegrant)
• Crospovidone – 2 to 5% (as a disintegrant)
• Hydroxypropyl cellulose – 2 to 6% (as a binder)
• Hydroxypropyl cellulose – 15 to 35% (as an extended release polymer)
• Hydroxypropyl Cellulose, Low-substituted – 5 to 50% (as a binder or disintegrant)
• Hypromellose (HPMC) - 2 to 5% (as a binder)
• Hypromellose (HPMC) – 10 to 80% % (as matrix forming agent)
• Lactose, Monohydrate - amount may vary (as a diluent)
• Lactose, Spray-Dried - amount may vary (as a diluent for moisture sensitive product)
• Magnesium Stearate – 0.25 to 5% (as a lubricant)
• Mannitol – 10 to 90% (as a diluent)
• Microcrystalline cellulose – 20 to 90% (as a diluent)
• Microcrystalline cellulose – 5 to 15% (as a disintegrant)
• Poloxamer – 0.01 to 5% (as wetting agent)
• Povidone – 0.5 to 5% (as a binder)
• Pregelatinized starch – 5 to 75% (as a diluent)
• Pregelatinized starch – 5 to 20% (as a binder)
• Pregelatinized starch – 5 to 10% (as a disintegrant)
• Saccharin – 0.02 to 0.5% (as a sweetening agent)
• Silicified Microcrystalline cellulose - amount may vary (as a filler)
• Stearic Acid – 1 to 3% (as a lubricant)
• Talc – 1 to 10% (as a glidant and lubricant)
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