# Machine Capacity Calculation in Pharmaceutical Industry

To determine the capacity in kgs the volume of machine and density of a powder are to be measured and then multiplied by Liters. Capacity in term of liters remain fix but in kgs vary depending upon density of powder. For maximum capacity usually 60-70% of machine is considered and results are to be validated. For minimum capacity usually 30-40% of machine is considered and results are to be validated.

#### For Rapid Mixer Granulator

Maximum Machine Capacity Calculation

Determine capacity in term of liters, for this add measured volume water in RMG.

Say it is 500 liters,

If density of powder is 0.75; then the volume of RMG will be 500×0.75=375 kg,

Now, 70% of it is = 375×70/100 = 262.50 kg,

So, the maximum capacity of RMG is 262.50 kg.

Minimum Machine Capacity Calculation

Determine capacity in term of liters, for this add measured volume water in RMG.

Say it is 500 liters,

If density of powder is 0.75; then the volume of RMG will be 500×0.75=375 kg,

Now, 40% of it is = 375×40/100 = 150.00 kg,

So, the minimum capacity of RMG is 150.00 kg.

#### For Coating Pan Capacity Calculation

Maximum capacity of the pan is calculated by the brim volume and the bulk density of the tablets.

Thus, Maximum Capacity of Coating Pan = Brim volume of pan (ltrs) x Bulk density of tablets (g/ml)

Let,

Brim volume = 300 ltrs.

Bulk density of tablets = 0.72 g/ml

Maximum capacity of coating pan = 300 x 0.72 = 216.0 Kg

If 60% of the maximum capacity is the minimum capacity of coating pan.

Minimum capacity of coating pan = 216.0 × 60% = 129.6 kg

Note:

• The coating pan's brim volume determines the coating machine's operational capacity.
• Bulk density depends on the tablet shape and size.

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