Creatinine Clearance Calculation Formula

The creatinine clearance test is a clinical test to check the kidney function. It is also called a serum creatinine test, is a way for doctors to measure how well your kidneys are working.


Creatinine Clearance = ((Urine Creatinine × Days Urine Volume) ÷ (Serum Creatinine × 1440)

Creatinine Clearance Calculation by Mass

This equation is a simple re-write of the standard formula: Clearance = UV/P.


The volume term V is actually best represented as V dot (for flow), with units of mL/min.

The term UV is the mass of creatinine excreted in one day.

The constant 0.0144 is a properly scaled version of the number of minutes in one day: 1440


Creatinine Clearance = (Urine Creatinine Mass at 24 Hours ÷ Serum Creatinine Concentration) ÷ 0.0144

Creatinine Clearance Calculation by Cockcroft-Gault Equation

Creatinine Clearance = Sex × ((140 - Age) / (Serum Creatinine)) × (Weight / 72)

  • Where, Sex = For Female (0.85) & For Male (1)





  1. Kindly add an example for ease of understanding


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